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    新疆福彩25选七走势图:Compression, Binding and Disintegrating Agents

    新疆福彩25选七 www.nwxy.net The solid oral form is still the most common form in today’s pharmaceutical industry, due to its many benefits. When manufacturing solid products designed for oral administration, certain aspects must be considered:
    - the direct compression or capsule-filling process requires excellent flow and good compressibility of the mix;
    - the finished products must be chemically and physically robust and stable enough over time;
    - the finished products must be capable of releasing the active ingredient once ingested.

    Products

    SEPPIC offers a wide range of binding, disintegrating and compression agents designed for the manufacturing of tablets and capsules:

    • SEPISTAB? ST 200
    • L-HPC
    • HARMACOAT?
    • SEPITRAP?
    • NEUSILIN?
    • CEOLUS?

    Binding agents

    Compression is the cold compaction of the various components of the tablet. The role of the binding agent is to bring cohesion to the mix of powders and thus produce tablets with acceptable hardness and friability.

    The binding excipient can be used dry for direct compression processes, or in aqueous medium for wet granulation processes.

    Binding agents that can be used in direct compression have very high cohesive properties. Binding agents that can be used in wet granulation are soluble in water. They are used to wet the mix of powders which is then granulated.

    Low-viscosity Hypromellose (HPMC), HydroxyPropyl Cellulose (HPC), certain grades of microcrystalline cellulose and even pregelatinized corn starch are among the most widely used binding agents.

    Disintegrating agents

    Disintegrating agents accelerate the swelling or disintegration of a tablet once it comes into contact with a fluid.

    Disintegrating agents can be added before or after the wet granulation stage. If the disintegrating agent is added before granulation (intragranular phase), the particles will be finer. If the disintegrating agent is added after granulation (extragranular phase), this improves disaggregation. The excipient can also be added in both phases.

    Low-substituted HydroxyPropyl Cellulose (HPC) and even pregelatinized corn starch are among the most widely used disintegrating agents.

    Compression agents

    In addition to the binding and disintegrating agents already mentioned, SEPPIC markets compression agents. These agents are used in the tablet’s composition and can have a variety of functions, including bulking agents, powder solubilizers, sweeteners, mixes for orally disintegrating tablets, stabilizers, etc.

  •  [生活资讯]  [辣妹探店]  [激情试驾]  [创客餐考] 2019-10-21
  • 目前的缓和,是美国中期选举特郎普需要外交得分。 2019-10-17
  • 西安紫云溪小区深夜有人竟高空扔粪便 律师:违法行为 2019-10-17
  • 研究显示刷社交软件加剧中年焦虑 对青年影响较弱 2019-10-14
  • 蔡依林今日发布新歌“我对我”宣告音乐态度蔡依林 2019-10-14
  • 贸易战一旦开启,要做好大批企业倒闭、失业率上升的充分准备。底线思维。 2019-10-10
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  • 【“文化遗产”那些事儿】中国首个入选世界非遗的节日:端午习俗你知几个? 2019-10-09
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  • 社会主义社会按劳分配是建立在公有制和私有制并存基础上的,共产主义社会按需分配是建立在公有制基础上的,所有制基础不同,其分配形式也就不同。所谓“共产主义... 2019-10-02
  • 年龄大了,也想积点口德,已经给你笔下留情了。 2019-09-24
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