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    新疆福彩35选7最新开奖:Modified Release and Taste Masking

    新疆福彩25选七 www.nwxy.net NCEs (New Chemical Entities) are difficult to formulate since most of them are poorly water-soluble. Reformulation of existing actives is also a trend.
    Improvement of drug efficiency, bioavailability, safety, reduction of toxicity and side effects, controlled release are some key parameters for formulators.

    More and more, pharmaceutical laboratories wish to develop new finished dosage forms targeting specific populations such as children and elderly people. Formulators are therefore seeking to develop pharmaceutical formulations with new galenics and innovative textures.

    Modified release forms include:

    • Controlled release
    • Delayed release
    • Immediate or fast release (for orodispersible tablets)
    • Targeted release (enteric)

    With the growing interest for orodispersible tablets (ODTs), taste masking is also a key parameter.

    Modified Release

    www.nwxy.netmercializes excipients to develop controlled release forms:

    • To facilitate the adsorption of the drugs by the organism, actives must be released in the intestine and therefore protected from an early release inside the stomac thanks to an enteric coating.
    • The use of a sustained release agent like hypromellose is efficient to obtain a sustained release of an active.
    • In some cases, release of an active in the mouth is necessary. In that case, orodispersible tablets (ODTs) can be formulated with disintegrants to obtain a fast and efficient release.


    SEPPIC offers a range of products: Metolose SR, AQOAT to formulate modified release formulations.
    SEPPIC also offers mixes of lipidic excipients for prilling and Hot Melt Coating processes to formulate sustained release solutions.

    Taste masking

    When a solid dosage form is formulated, its taste should be considered. This parameter is even more important for forms that are disintegrated and stayed longer in the oral cavity (i.e orodispersible tablets (ODTs)).

    www.nwxy.netmercializes products for taste masking: REBATEN?and F-MELT?which help to develop solid oral forms of active ingredients with a bad taste.

    SEPPIC offers also mixs of lipidic excipients for prilling and Hot Melt Coating processes to fomulate active ingredients with a bad taste.

  • 进京通行证限次数!70.9万辆本地化使用外埠号牌车或将受影响 2019-02-15
  • 电视剧《半生缘》“命运版”海报出炉 2019-02-15
  • 湖南官员办公室纵火身亡 因投资亏损与他人纠纷 2019-02-05
  • 河北省对中央环保督察“回头看”问题整改进行部署 强化标本兼治 防止整改问题反弹 2019-02-04
  • 全面深化改革开放 海南如何成新标杆(政策解读) 2019-02-04
  • 过端午到沁县 观龙舟竞赛 2019-01-29
  • 好坏大家判 事事有人管 2019-01-29
  • 麻建军:认真做好每件事 2019-01-29
  • 西藏:雪域高原唱响教育歌 2019-01-22
  • 国家开发银行获第十二届人民企业社会责任奖年度企业奖 2019-01-22
  • 文瀛公园第二届百合花展 2019-01-20
  • 一笔“农”墨绘山川——重庆市万州区国家农业公园速写 2019-01-02
  • 李劭凯:今天我们为什么读《孟子》 2019-01-02
  • 诺基亚刘海屏新机曝光 4月27日线上开卖 2018-12-30
  • 苏州大学研究生支教团网上众筹资助留守儿童 2018-12-27