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    福建体彩31选7走势图:Route of Administration

    新疆福彩25选七 www.nwxy.net SEPPIC offers excipients for the different routes of administration

    Pharmaceutical drugs are developed for 3 main routes of administration: oral, injectable and topical routes. Oral route accounts for the majority of the pharmaceutical market, followed by injectable and then topical drugs. Each route of administration has its own advantages and disadvantages, as well as specific requirements.

    Oral route

    The oral route presents major benefits such as the ease of use (like tablets & capsules). These forms are usually cost efficient and can be used to formulate modified release systems which can improve bioavailability. Improving drug performance and safety is key for oral route.

    SEPPIC designs and manufactures a wide range of excipients such as coatings, binders, fillers, disintegrants, solubilizers, emulsifiers, dedicated to oral applications.

    Whatever oral forms developped (tablets, capsules, powder, syrups, gels…), formulators may use one or several SEPPIC excipients to improve bioavailability, stability, delivery, taste masking, compliance.

    SEPPIC pays a great attention to offer ready-to-use excipients with the highest grade of quality and follows the IPEC-GMP standards for all its excipients dedicated to oral route. SEPPIC was a pioneer in the EXCiPACT? standard certification and has been successfully audited and certified since 2013.

    Injectable route

    The injectable route is used for a quick administration (adapted to emergencies), a controlled dosage, the absence of intestinal and hepatic first pass effect and continuous medication (infusion). This route of administration is growing with the developments of biological drugs posing new challenges.

    SEPPIC designs and manufactures adjuvants for therapeutic vaccines and excipients such as solubilizers and emulsifiers dedicated to injectable route of administration.

    Whatever injectable drugs developed - biologicals or small molecules - and whatever the parenteral administration - intravenous, subcutaneous, ocular - drugs can be developed with one or several SEPPIC products to improve solubility, stability, safety and efficiency of pharmaceutical actives.

    SEPPIC excipients are manufactured with the same high quality standards as for active pharmaceutical ingredients. Injectable excipients comply with the GMP Part II guidelines and current pharmacopoeias. Adjuvants dedicated to therapeutic vaccines are manufactured under aseptic conditions in a pharmaceutical facility and comply with GMP Part I guidelines.

    Topical route

    The topical route is easy to use for patients. It can also be used for a local effect and has no first pass effect, which can be of great benefit in reducing side effects of oral dosage forms. Challenges of this route of administration are linked to the texture of the drug to improve patient compliance as well as efficacy.

    SEPPIC designs and manufactures excipients such as emulsifiers, solubilizers and texturing agents for the topical route of administration to help formulators optimize and simplify their formulations.

    There is a wide range of topical forms. The most common ones are gels and creams but other formulas exist and can be excellent drug vehicles: foams, spray, patches, cream gels.

    The main challenges for formulating topical forms are Active Pharmaceutical Ingredient (API) solubility, stability of the formulation, penetration of the API, formulation of a combination of APIs, patient compliance.

    Topical excipients follow GMP-IPEC guidelines and are EXCiPACT? certified.

  • 女性之声——全国妇联 2019-04-02
  • 女性之声——全国妇联 2019-03-28
  • 2018国际排联世界沙滩排球巡回赛海阳公开赛球场竣工 2019-03-28
  • 西安七旬老人拄拐到高考志愿咨询会 帮孙子看看报啥学校 2019-03-21
  • 人民日报社天津分社公开招聘工作人员公告 2019-03-21
  • 学者:“感应舍利”的出现为何是“必然” 2019-03-20
  • 卡布的专栏作者中国国家地理网 2019-03-20
  • 美国又打出2000亿关税牌,中方这300字声明暗藏玄机! 2019-03-05
  • 新余市二单位6名领导干部被纪委通报 2019-03-04
  • 图解:中国经济已现一大积极信号,你知道了吗? 2019-03-03
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  • 昆明一直升飞机在执行任务中失事 3名机组人员全部遇难 2019-02-18
  • “习近平社会治理法治思想”的核心要义及其时代价值 2019-02-17