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    福建体彩31选7走势图:Route of Administration

    新疆福彩25选七 www.nwxy.net SEPPIC offers excipients for the different routes of administration

    Pharmaceutical drugs are developed for 3 main routes of administration: oral, injectable and topical routes. Oral route accounts for the majority of the pharmaceutical market, followed by injectable and then topical drugs. Each route of administration has its own advantages and disadvantages, as well as specific requirements.

    Oral route

    The oral route presents major benefits such as the ease of use (like tablets & capsules). These forms are usually cost efficient and can be used to formulate modified release systems which can improve bioavailability. Improving drug performance and safety is key for oral route.

    SEPPIC designs and manufactures a wide range of excipients such as coatings, binders, fillers, disintegrants, solubilizers, emulsifiers, dedicated to oral applications.

    Whatever oral forms developped (tablets, capsules, powder, syrups, gels…), formulators may use one or several SEPPIC excipients to improve bioavailability, stability, delivery, taste masking, compliance.

    SEPPIC pays a great attention to offer ready-to-use excipients with the highest grade of quality and follows the IPEC-GMP standards for all its excipients dedicated to oral route. SEPPIC was a pioneer in the EXCiPACT? standard certification and has been successfully audited and certified since 2013.

    Injectable route

    The injectable route is used for a quick administration (adapted to emergencies), a controlled dosage, the absence of intestinal and hepatic first pass effect and continuous medication (infusion). This route of administration is growing with the developments of biological drugs posing new challenges.

    SEPPIC designs and manufactures adjuvants for therapeutic vaccines and excipients such as solubilizers and emulsifiers dedicated to injectable route of administration.

    Whatever injectable drugs developed - biologicals or small molecules - and whatever the parenteral administration - intravenous, subcutaneous, ocular - drugs can be developed with one or several SEPPIC products to improve solubility, stability, safety and efficiency of pharmaceutical actives.

    SEPPIC excipients are manufactured with the same high quality standards as for active pharmaceutical ingredients. Injectable excipients comply with the GMP Part II guidelines and current pharmacopoeias. Adjuvants dedicated to therapeutic vaccines are manufactured under aseptic conditions in a pharmaceutical facility and comply with GMP Part I guidelines.

    Topical route

    The topical route is easy to use for patients. It can also be used for a local effect and has no first pass effect, which can be of great benefit in reducing side effects of oral dosage forms. Challenges of this route of administration are linked to the texture of the drug to improve patient compliance as well as efficacy.

    SEPPIC designs and manufactures excipients such as emulsifiers, solubilizers and texturing agents for the topical route of administration to help formulators optimize and simplify their formulations.

    There is a wide range of topical forms. The most common ones are gels and creams but other formulas exist and can be excellent drug vehicles: foams, spray, patches, cream gels.

    The main challenges for formulating topical forms are Active Pharmaceutical Ingredient (API) solubility, stability of the formulation, penetration of the API, formulation of a combination of APIs, patient compliance.

    Topical excipients follow GMP-IPEC guidelines and are EXCiPACT? certified.

  • 辽阔疆域 风光无限 昭苏·巴勒克苏大草原 2019-06-18
  • (原创)取消“份子钱”是出租车改革必须迈出的一步 2019-06-18
  • 【一周反腐】河南、上海、重庆等地多名厅级干部被查 2019-06-15
  • 武汉拟扩大公租房轮候期间应保尽保范围 2019-06-14
  • 日本积极筹划“安金会” 日朝已在蒙古进行接触 2019-06-12
  • 【理上网来·辉煌十九大】续写脱贫攻坚、有效扶贫新篇章 2019-06-12
  • 笑博士这是从哪里掺来的东西?社会主义企业计划,是国民经济计划的一个组成部分,是服从于国家计划的战略要求的。笑博士搞的这个规划提纲,仅仅是私有制企业的规划提纲,与 2019-06-06
  • 金正恩乘机赴新加坡半路突改航班号、目的地?答案来了! 2019-06-02
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  • 国内首届GMF电竞音乐节将在深举行 2019-06-01
  • 《绝代双骄》制作特辑曝光 匠心巨献演绎现世武侠 2019-05-31
  • 人民的力量——一份大报,与一个大党、一个大国的故事 2019-05-22
  • 寿慧生:浅析中美经贸关系的“行稳致远”时期 2019-05-22
  • 铁路迎端午客流最高峰 今日预计发送旅客1318万人次 2019-05-21