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    双色球基本走势图表图:Route of Administration

    新疆福彩25选七 www.nwxy.net SEPPIC offers excipients for the different routes of administration

    Pharmaceutical drugs are developed for 3 main routes of administration: oral, injectable and topical routes. Oral route accounts for the majority of the pharmaceutical market, followed by injectable and then topical drugs. Each route of administration has its own advantages and disadvantages, as well as specific requirements.

    Oral route

    The oral route presents major benefits such as the ease of use (like tablets & capsules). These forms are usually cost efficient and can be used to formulate modified release systems which can improve bioavailability. Improving drug performance and safety is key for oral route.

    SEPPIC designs and manufactures a wide range of excipients such as coatings, binders, fillers, disintegrants, solubilizers, emulsifiers, dedicated to oral applications.

    Whatever oral forms developped (tablets, capsules, powder, syrups, gels…), formulators may use one or several SEPPIC excipients to improve bioavailability, stability, delivery, taste masking, compliance.

    SEPPIC pays a great attention to offer ready-to-use excipients with the highest grade of quality and follows the IPEC-GMP standards for all its excipients dedicated to oral route. SEPPIC was a pioneer in the EXCiPACT? standard certification and has been successfully audited and certified since 2013.

    Injectable route

    The injectable route is used for a quick administration (adapted to emergencies), a controlled dosage, the absence of intestinal and hepatic first pass effect and continuous medication (infusion). This route of administration is growing with the developments of biological drugs posing new challenges.

    SEPPIC designs and manufactures adjuvants for therapeutic vaccines and excipients such as solubilizers and emulsifiers dedicated to injectable route of administration.

    Whatever injectable drugs developed - biologicals or small molecules - and whatever the parenteral administration - intravenous, subcutaneous, ocular - drugs can be developed with one or several SEPPIC products to improve solubility, stability, safety and efficiency of pharmaceutical actives.

    SEPPIC excipients are manufactured with the same high quality standards as for active pharmaceutical ingredients. Injectable excipients comply with the GMP Part II guidelines and current pharmacopoeias. Adjuvants dedicated to therapeutic vaccines are manufactured under aseptic conditions in a pharmaceutical facility and comply with GMP Part I guidelines.

    Topical route

    The topical route is easy to use for patients. It can also be used for a local effect and has no first pass effect, which can be of great benefit in reducing side effects of oral dosage forms. Challenges of this route of administration are linked to the texture of the drug to improve patient compliance as well as efficacy.

    SEPPIC designs and manufactures excipients such as emulsifiers, solubilizers and texturing agents for the topical route of administration to help formulators optimize and simplify their formulations.

    There is a wide range of topical forms. The most common ones are gels and creams but other formulas exist and can be excellent drug vehicles: foams, spray, patches, cream gels.

    The main challenges for formulating topical forms are Active Pharmaceutical Ingredient (API) solubility, stability of the formulation, penetration of the API, formulation of a combination of APIs, patient compliance.

    Topical excipients follow GMP-IPEC guidelines and are EXCiPACT? certified.

  • 进京通行证限次数!70.9万辆本地化使用外埠号牌车或将受影响 2019-02-15
  • 电视剧《半生缘》“命运版”海报出炉 2019-02-15
  • 湖南官员办公室纵火身亡 因投资亏损与他人纠纷 2019-02-05
  • 河北省对中央环保督察“回头看”问题整改进行部署 强化标本兼治 防止整改问题反弹 2019-02-04
  • 全面深化改革开放 海南如何成新标杆(政策解读) 2019-02-04
  • 过端午到沁县 观龙舟竞赛 2019-01-29
  • 好坏大家判 事事有人管 2019-01-29
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  • 西藏:雪域高原唱响教育歌 2019-01-22
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  • 文瀛公园第二届百合花展 2019-01-20
  • 一笔“农”墨绘山川——重庆市万州区国家农业公园速写 2019-01-02
  • 李劭凯:今天我们为什么读《孟子》 2019-01-02
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  • 苏州大学研究生支教团网上众筹资助留守儿童 2018-12-27