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    新疆35选7走势图:Route of Administration

    新疆福彩25选七 www.nwxy.net SEPPIC offers excipients for the different routes of administration

    Pharmaceutical drugs are developed for 3 main routes of administration: oral, injectable and topical routes. Oral route accounts for the majority of the pharmaceutical market, followed by injectable and then topical drugs. Each route of administration has its own advantages and disadvantages, as well as specific requirements.

    Oral route

    The oral route presents major benefits such as the ease of use (like tablets & capsules). These forms are usually cost efficient and can be used to formulate modified release systems which can improve bioavailability. Improving drug performance and safety is key for oral route.

    SEPPIC designs and manufactures a wide range of excipients such as coatings, binders, fillers, disintegrants, solubilizers, emulsifiers, dedicated to oral applications.

    Whatever oral forms developped (tablets, capsules, powder, syrups, gels…), formulators may use one or several SEPPIC excipients to improve bioavailability, stability, delivery, taste masking, compliance.

    SEPPIC pays a great attention to offer ready-to-use excipients with the highest grade of quality and follows the IPEC-GMP standards for all its excipients dedicated to oral route. SEPPIC was a pioneer in the EXCiPACT? standard certification and has been successfully audited and certified since 2013.

    Injectable route

    The injectable route is used for a quick administration (adapted to emergencies), a controlled dosage, the absence of intestinal and hepatic first pass effect and continuous medication (infusion). This route of administration is growing with the developments of biological drugs posing new challenges.

    SEPPIC designs and manufactures adjuvants for therapeutic vaccines and excipients such as solubilizers and emulsifiers dedicated to injectable route of administration.

    Whatever injectable drugs developed - biologicals or small molecules - and whatever the parenteral administration - intravenous, subcutaneous, ocular - drugs can be developed with one or several SEPPIC products to improve solubility, stability, safety and efficiency of pharmaceutical actives.

    SEPPIC excipients are manufactured with the same high quality standards as for active pharmaceutical ingredients. Injectable excipients comply with the GMP Part II guidelines and current pharmacopoeias. Adjuvants dedicated to therapeutic vaccines are manufactured under aseptic conditions in a pharmaceutical facility and comply with GMP Part I guidelines.

    Topical route

    The topical route is easy to use for patients. It can also be used for a local effect and has no first pass effect, which can be of great benefit in reducing side effects of oral dosage forms. Challenges of this route of administration are linked to the texture of the drug to improve patient compliance as well as efficacy.

    SEPPIC designs and manufactures excipients such as emulsifiers, solubilizers and texturing agents for the topical route of administration to help formulators optimize and simplify their formulations.

    There is a wide range of topical forms. The most common ones are gels and creams but other formulas exist and can be excellent drug vehicles: foams, spray, patches, cream gels.

    The main challenges for formulating topical forms are Active Pharmaceutical Ingredient (API) solubility, stability of the formulation, penetration of the API, formulation of a combination of APIs, patient compliance.

    Topical excipients follow GMP-IPEC guidelines and are EXCiPACT? certified.

  •  [生活资讯]  [辣妹探店]  [激情试驾]  [创客餐考] 2019-10-21
  • 目前的缓和,是美国中期选举特郎普需要外交得分。 2019-10-17
  • 西安紫云溪小区深夜有人竟高空扔粪便 律师:违法行为 2019-10-17
  • 研究显示刷社交软件加剧中年焦虑 对青年影响较弱 2019-10-14
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  • 贸易战一旦开启,要做好大批企业倒闭、失业率上升的充分准备。底线思维。 2019-10-10
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  • 年龄大了,也想积点口德,已经给你笔下留情了。 2019-09-24
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  • 溃疡恶变也会腹痛 这些肿瘤最容易被误诊 2019-09-24
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